COURSE DESCRIPTION

The course  builds on  Biochemistry I and addresses chemical concepts that govern the  structure and functioning of biological molecules; gene function and expression; molecular tools in medical research  and  development;  biochemical  pathways  in  metabolism  of  biological  molecules.  It  also covers protocols for assessing the normal function of the liver and kidneys.

COURSE OBJECTIVES

Upon completion of the course, the student will:

a)  Understand chemicals that govern structure and function of biological molecules.

b)  Be equipped with knowledge about Gene function and expression;

c)  Be able to explain and describe the genesis of the various hereditary disorders.

d)  Be able to exploit the various molecular tools in medical research and development.

e)  Appreciate biochemical pathways involved in the metabolism of biological molecules

f)  Explain the occurrence of some of the common inborn errors in metabolism.

g)  Have practical knowledge on assessment of normal function of human liver and kidney

h) Explain how genetic information is transferred from one generation to another and how it is expressed to form proteins

i) Explain the immunological basis for immunization/vaccination

 EXPECTED OUTCOMES

The student will have learnt  about the chemical and molecular mechanisms underlying the functions of the body, metabolic and regulatory processes, and mechanisms that govern inheritance in molecules in medical science which is essential to any practice of healing arts and the relief of human suffering in nursing practice.

REFERENCES

1)  Berg, JM, Tymoczko, JL, & Stryer, L. (2006).  Biochemistry: Int’l Ed.: W.H. Freeman

2)  Lehninger A.L & Nelson D.L. (2008). Lehninger Principles of Biochemistry: Worth Publishers.

3)  Murray R.K, Rodwell, VV, Bender, D & Botham, KM. (2009).Harper's Illustrated Biochemistry.

New York: McGraw-Hill

4)  Sawhney, SK & Singh, R, (2005) Introductory Practical Biochemistry. Kolkata: Alpha Science.

5)  Anthikad J. (2005). Biochemistry for Nurses. Kolkata: Jaypee Brothers Medical Publishers